One of the most common types of cancer worldwide is colorectal cancer, sometimes known as colon cancer. Even though the precise reason isn’t always known, there are various risk factors that we can manage. The colon or rectum are common sites. Maintaining your general health requires being proactive in reducing your risk for colorectal cancer. If you or your loved ones also have colorectal cancer and want to consult with the finest doctors, then you should consult with Oncoplus. As our specialists provide the finest colorectal cancer treatment in Delhi, India. So here we’ll look at six practical strategies to lower your risk and safeguard yourself from this potentially fatal illness in this blog.
Six practical strategies to reduce your risk:
Your diet is one of the most essential factors raising your risk of colorectal cancer. You may dramatically lower your risk by eating a diet high in fruits, vegetables, and whole grains and avoiding processed foods, red meat, and saturated fats. These food options can support healthy weight maintenance and encourage regular bowel movements, both of which are essential for preventing colorectal cancer. The vitamins, minerals, and antioxidants found in fruits and vegetables can help shield the cells lining your colon and rectum against deterioration that might cause cancer. Whole grains, beans, and lentils are examples of fibre-rich meals that can help with digestion and reduce constipation, which shortens the time hazardous compounds are in contact with your intestinal walls.
Read More : How Your Dietary Habit Influence Cancer Disease
Another crucial component of preventing colorectal cancer is regular physical activity. Maintaining a healthy weight and reducing inflammation in the body, which is connected to the emergence of cancer, are made possible by engaging in moderate to intense exercise for at least 150 minutes every week. Additionally, exercise encourages regular bowel movements and improves immune system performance, which enables your body to identify and get rid of potentially hazardous cells more quickly. It’s essential to incorporate an exercise you enjoy into your routine, whether it’s jogging, swimming, dancing, or even gardening.
Read More: Physical Activity And Cancer Risk
Obesity and being overweight are known risk factors for colorectal cancer. Extra body fat, especially in the abdomen, can lead to hormonal changes and inflammation that raise the risk of developing cancer. Any weight loss, no matter how minor, can significantly reduce your risk. To reach and maintain a healthy weight, make an effort to eat a balanced diet and to exercise frequently. A certified dietician or healthcare expert can offer you individualised advice and support as you embark on your weight loss journey.
Smoking and alcohol use are both significantly linked to a higher risk of colorectal cancer. It’s recommended to either limit or altogether avoid drinking in order to reduce your risk. If you do decide to drink, limit yourself to modest amounts up to one drink for women and two for men every day. On the other hand, smoking not only increases your chance of colorectal cancer but also contributes significantly too many other cancers and chronic illnesses. One of the most effective actions you can take to improve your general health and prevent cancer is to stop smoking. To help you permanently break the habit, look for assistance and resources.
The key to successful treatment and survival for colorectal cancer is early identification. Regular screenings, such as colonoscopies, can find cancer or precancerous polyps when they are still treatable and curable in their early stages. It’s important to discuss your screening choices with your healthcare provider because screening recommendations change depending on your age, family history, and other risk factors. In general, people at average risk should start getting screened around 45 or sooner if they have certain risk factors. As early detection could save your life, don’t put off scheduling a screening.
It has been observed that colon cancer tends to run in families. Your risk may be higher if the disease runs in your family. Knowing your family’s medical history and sharing it with your doctor are both very important. They are better equipped to determine your risk and suggest the proper screenings and preventive steps.
In determination, a proactive method to safeguard your health and improve your chances of living a long and cancer-free life is taking measures to reduce your risk for colorectal cancer. You may dramatically lower your risk of contracting this potentially fatal disease by adopting a balanced diet, becoming physically active, maintaining a healthy weight, limiting alcohol use, stopping smoking, receiving routine screenings, and understanding your family history. Remember that early detection and prevention are effective weapons in the fight against colorectal cancer; as such, include these behaviours in your daily routine and urge your loved ones to do the same. The work is worthwhile for your health and well-being.
Cervical cancer is a severe health issue and is diagnosed in more than 500,000 women in a year. It also causes the death of more than 300,000 people worldwide. The uterus and vagina are connected by the cervix, which is where cervical cancer usually develops. The Human Papillomavirus (HPV), a sexually transmitted infection, is the leading cause of most cervical cancers. In most cases, the immune system prevents HPV from causing harm when it is present in the body. The virus, however, can survive for years in a small percentage of people. Some cervical cells are now more prone to develop into cancerous cells. Fortunately, routine Pap tests have shown to be a reliable method of detecting and preventing cervical cancer. However, how often should you have a Pap test? Here we’ll discuss the significance of Pap tests, the suggested timing for getting tested, and why being cautious is essential for preserving women’s health in this blog.
Understanding Pap Tests:
The purpose of a Pap test, sometimes referred to as a Pap smear, is to collect cells from the cervix and examine them for anomalies. If untreated, these anomalies could develop into cervical cancer. Early detection of alterations in the cervix’s cells is the goal of the test, which will enable prompt intervention and prevention.
Why Regular Pap Tests Matter:
Regular Pap tests are essential for avoiding cervical cancer for several reasons, including the following mention below:
Recommended Pap Test Frequency:
As medical knowledge and technology have advanced over time, the recommended Pap test frequency has changed. Medical organizations’ recommendations are based on things like age, risk factors, and the results of prior tests, as discussed below:
A robust weapon in the fight against cervical cancer is routine Pap testing in conclusion. Early abnormal cell detection offers the chance for prompt action and prevention. The best method to ensure the healthiest cervical tissue is to be aware and discuss your screening plan with a healthcare practitioner. Guidelines on the frequency of Pap tests may vary depending on age and risk factors as discussed above. Always prioritize routine checkups because prevention is the key to maintaining your well-being. Or else talk to your doctor about when you should undergo Pap and HPV screening tests so that you don’t miss out on this possibly life-saving chance. If you are also concerned about your health and want to consult with the best cancer specialists, then you should consult with Oncoplus, the finest cancer specialist in Delhi, India. At Oncoplus, we are the first-of-its-kind dedicated cancer care unit following international protocols. The scope of our services is designed to deliver a holistic treatment and diagnosis platform. We are working with social security schemes of India to create a vision of cancer free and cancer conscious India. So let’s fight cancer together and live a happy and healthy life.
Ewing sarcoma is a rare, aggressive form of bone cancer primarily affecting children and young adults. The disease is named after Dr James Ewing, who first described it in 1921. While chemotherapy and radiation therapy can be effective in treating Ewing sarcoma, many patients experience relapse or resistance to these treatments, highlighting the need for new therapeutic targets. Recent research has identified the ETV6 protein as a potential target for Ewing sarcoma treatment. In this blog, we will discuss about Ewing sarcoma, its symptoms, treatments and how ETV6 protein can be an essential target for Ewing sarcoma treatment in Delhi, India.
What is Ewing Sarcoma?
Ewing Sarcoma is most commonly found in children and young adults and is often diagnosed in people between the ages of 10 and 20. Children and teenagers are more likely to develop the rare bone and soft tissue cancer known as Ewing sarcoma, sometimes referred to as Ewing’s sarcoma and Ewing tumour. When the DNA in some cells alters, aberrant cells that attack healthy tissue are created, leading to Ewing sarcoma. More information about the relationship between cell alterations and Ewing sarcoma is being discovered. New Ewing sarcoma treatments are being tested in clinical trials because of this research, and these trials may be beneficial for young patients with Ewing sarcoma.
Symptoms of Ewing Sarcoma:
Symptoms of Ewing Sarcoma can vary depending on the location of the tumour but can include:
Ewing Sarcoma Treatments:
Treatments for Ewing Sarcoma typically involve a combination of chemotherapy, radiation therapy, and surgery. The specific treatment plan will depend on the size and location of the tumor, as well as the stage of the cancer.
Chemotherapy is often the first line of treatment and involves the use of drugs to kill cancer cells. The tumour is reduced in size and any leftover cancer cells are eradicated with radiation therapy. Surgery may be necessary to remove the tumor or affected bone, and can be followed by reconstructive surgery if necessary. In some cases, a stem cell transplant may be recommended after chemotherapy or radiation therapy to help restore the body’s blood cells and immune system.
Overall, early detection and prompt treatment are crucial for improving outcomes for those with Ewing Sarcoma. If you have concerns or questions about Ewing Sarcoma or any other health condition, it is important to speak with a qualified healthcare provider.
What is ETV6 Protein?
ETV6 is a transcription factor, a protein that regulates the expression of other genes. It is involved in a variety of cellular processes, including cell proliferation, differentiation, and apoptosis. ETV6 has been implicated in several types of cancer, including leukemia, lymphoma, and solid tumors such as prostate cancer and breast cancer. However, its role in Ewing sarcoma has only recently been discovered.
In a study published in the journal Cancer Cell, researchers found that ETV6 is essential for the growth and survival of Ewing sarcoma cells. The researchers used CRISPR-Cas9 gene editing technology to disrupt the ETV6 gene in Ewing sarcoma cell lines. They found that when ETV6 was knocked out, the cells stopped proliferating and underwent apoptosis, a process of programmed cell death. These results suggest that targeting ETV6 could be an effective strategy for treating Ewing sarcoma.
The researchers also investigated the mechanism by which ETV6 promotes Ewing sarcoma growth. They found that ETV6 regulates the expression of genes involved in several key cellular processes, including cell cycle progression, DNA damage repair, and metabolism. By controlling these processes, ETV6 enables Ewing sarcoma cells to survive and proliferate in the hostile environment of the tumor microenvironment.
The researchers further demonstrated the therapeutic potential of targeting ETV6 in Ewing sarcoma by using a small molecule inhibitor called TK216. TK216 was designed to block the interaction between ETV6 and another protein called RNA polymerase II, which is involved in the transcription of DNA into RNA. The researchers found that TK216 inhibited the growth of Ewing sarcoma cells in vitro and in vivo, without affecting normal cells. Importantly, TK216 also showed synergy with standard chemotherapy drugs used to treat Ewing sarcoma, suggesting that it could be used in combination with these drugs to enhance their efficacy.
In conclusion, the discovery of ETV6 as a potential therapeutic target for Ewing sarcoma is a significant breakthrough in the field of cancer research. The findings of this study provide a foundation for the development of new drugs that target ETV6 and could improve treatment outcomes for Ewing sarcoma patients. The use of TK216, a small molecule inhibitor of ETV6, shows promise as a potential treatment for Ewing sarcoma and warrants further investigation. As more is learned about the role of ETV6 in Ewing sarcoma, it could also serve as a valuable biomarker for diagnosis and monitoring of this devastating disease. With advancements in medical technology and the availability of highly trained oncology surgeons in Delhi patients suffering from this rare form of cancer have access to world-class treatment options.
Bone marrow is a soft, spongy tissue found in the center of the majority of bones. Multiple myeloma cancer, leukemia, and lymphoma are all cancers that can develop in the bone marrow. Stem cells in bone marrow develop into various types of blood cells, including:
Red blood cells transport oxygen and carbon dioxide throughout the body;
white blood cells fight infection; and platelets aid in blood clotting.
When the body requires these blood cells, such as when old blood cells die, the body usually produces them. When these cells replicate too quickly, bone marrow cancer develops.
In this blog, we will look at the various types of bone marrow cancer, as well as their symptoms and treatment options.
Doctors identify bone marrow cancer based on the type of cell it affects in the body:
Multiple myeloma is a cancer that develops in the plasma cells of the bone marrow. Plasma cells are important components of the immune system because they produce antibodies that the body requires to fight foreign bacteria.
Cancers of the white blood cells are known as leukemias. These cancers can begin in other types of blood cells and then spread, or metastasize, into the bone marrow. Acute leukemias are cancers that grow quickly, whereas chronic leukemias grow slowly.
Cancer develops in the lymphocytes that circulate in the blood and lymph tissue after being produced in the bone marrow in people with lymphoma. Lymphoma can develop in a variety of locations throughout the body, including the bone marrow.
The type of treatment for bone marrow cancer is determined by a variety of factors, including the extent and type of cancer, as well as the patient’s age and overall health. A cancer care team will tailor treatment to the individual’s healthcare requirements.
Chemotherapy employs medications to either kill or prevent cancer cells from replicating. Chemotherapy treatment comes in a variety of forms. Chemotherapy is frequently administered by injection or via an intravenous (IV) drip by a cancer team. They will, however, occasionally give the individual oral medications instead.
This treatment involves delivering radiation directly to cancer cells in order to prevent them from multiplying and spreading. An oncologist, a cancer specialist, may use a machine that directs a high-powered radiation beam at the affected bone marrow.
If the cancer has spread to other parts of the body, the oncologist may advise total body irradiation. A specialized machine will be used by the cancer care team to immerse an individual in radiation. This irradiation is frequently used in conjunction with chemotherapy drugs as a preparation for a bone marrow transplant.
In some cases, a stem cell transplant may be an option, but not everyone with bone marrow cancer is a candidate for this type of treatment. Before the stem cells are administered via IV, a person will receive high doses of chemotherapy or radiation therapy to kill the existing bone marrow.