July is Bone Cancer Awareness Month! During July, we join hands to raise awareness, support research, and inspire hope for bone cancer survivors. So, let’s work together to raise awareness of this illness, inform others, and work towards a time when no one will have to battle bone cancer alone. Bone cancer is a relatively uncommon type of cancer that manifests inside the bones. Although it can affect any bone in the body, the long bones of the arms and legs are most frequently affected. As the signs of this type of cancer might match those of other disorders, it can be challenging to identify it early. For prompt intervention and better results, it is essential to understand the symptoms and signs of bone cancer and the various bone cancer treatments. Here in this blog, we will go through the signs and symptoms of bone cancer and practical cures.

 

Knowledge of Bone Cancer:

Primary and secondary bone cancer are the two basic types into which bone cancer can be divided. While secondary bone cancer, sometimes called metastatic bone cancer, spreads to the bone from other body regions, including the breast, lung, or prostate, primary bone cancer begins within the bone itself.

Depending on the location, stage, and kind of disease, the symptoms of bone cancer can change. Bone cancer may not exhibit any signs in its early stages. However, the following symptoms could appear when the tumour enlarges:

 

Options for Effective Treatment:

The method of treating bone cancer depends on a number of variables, including the disease’s type, stage, and location, as well as the patient’s general condition. For treating cancer, a multidisciplinary team of oncologists, orthopaedic surgeons, radiation oncologists, and other medical specialists usually works together to create a customized treatment plan. The following are some of the most typical bone cancer treatments:

 

In conclusion, excellent treatment outcomes depend on the early identification of bone cancer. You must get medical advice right away if you have chronic bone pain, swelling, or any other unsettling signs. Combinations of surgery, radiation therapy, chemotherapy, targeted therapy, and cutting-edge immunotherapy are frequently used to treat bone cancer. An individual’s ability to actively participate in their healthcare and increase the likelihood of a positive prognosis depends on how well-informed they are about the symptoms and available treatments. If you or your loved ones are suffering from bone cancer and want to fight against it, you should consult Oncoplus, the best hospital for bone cancer treatment. We take great satisfaction in being the greatest hospital for treating patients worldwide and battling this difficult illness. We provide individualized and comprehensive care that raises the bar for cancer thanks to state-of-the-art equipment and a team of recognized doctors. We can diagnose, treat, and monitor bone cancer with unmatched precision because our cutting-edge facilities give patients the best possible chance of recovery. Oncoplus walks you through every step of your recovery journey by fusing ground-breaking science with caring support. You may rely on us to provide unmatched knowledge and a better future.

Bone cancer can take place anywhere in the body, it normally affects the bones in the pelvis area or legs and arms, though cancer is quite rare it accounts to 1 percent of all cancers. Studies state that the noncancerous bone tumors are much more common than cancerous ones, the term doesn’t comprise of cancers, which begin somewhere else in the body and metastasize or spread to the bones, such cancers are termed for wherever they started in the body, for instance lung cancer, which spreads to the bones.

A few cancers take place only in children and others in adults. Oncologists normally surgically remove the cancer, but also use a combination of chemo and radiation therapy in treatment options. The option to use surgery, chemo or radiation therapy is purely based on the type and stage of bone cancer being treated. Consult with our specialist at Oncoplus Hospital, Defence Colony, if you experience symptoms such as unexplained weight loss, fatigue, bone pain, swelling and tenderness near the affected area and enfeebled bone, leading to stress fractures.

The reason for cancers of this type is not known, a few bone cancers have been linked to hereditary factors, while others are associated with previous radiation exposure. These cancers can be classified into different types based on the type of cell where the cancer began.

A few common kinds of bone cancer include; Osteosarcoma, which is the most common form of bone cancer. In this tumor, the cancerous cells produce bone, and occurs mostly among children and young adults, in the bones of the leg or arm. Chondrosarcoma is the second most common form of bone cancer in which the cancerous cells produce cartilage. It normally happens in the pelvis, legs or arms in middle-aged and older adults and Ewing Sarcoma tumors are commonly found in the pelvis, legs or arms of young adults and children.

It’s not clear what causes bone cancer, but experts opine a few factors, which are associated with an increased risk, including; Inherited genetic syndromes, Paget’s disease of bone and Radiation therapy for cancer. Exposure to radiation, which is given during radiation therapy for cancer, increases the risk of bone cancer in the future.

The treatment for this cancer (also known as bone sarcoma) depends on numerous factors including, the grade, type, location and size of the cancer as well the medical history, symptoms and personal preferences for treatment. Ewing sarcoma and Osteosarcoma can be treated with grouping chemotherapy, surgery and/or radiotherapy. Chondrosarcoma is normally treated with surgery alone. Learn more about cancers tele Consult with our best cancer doctors in India at Oncoplus Hospital, Defence Colony, New Delhi, write to us info@oncoplus.co.in or call us at +91 85889 09091 to book an appointment.

Cancer begins when cells grow out of control. Cells in any part of the body can become cancerous and spread (metastasise) to other parts.

Bone cancer is uncommon and starts when cells in the bone start to grow abnormally out of control. To understand bone cancer, it helps to know a little about normal bone tissue.

Most bones start out as softer, more flexible forms of tissue called cartilage and this cartilage later forms bones. In adults, cartilage is found at the end of some bones.

The bone itself has 2 kinds of cells.

Bones look as if they don’t change much, but they are very active. New bone is always forming while old bone is dissolving. This helps keeps bones strong. There are some other cells in the bone marrow like plasma cells and fibroblasts.

Any of these bone cells can develop into cancer.

Primary bone cancers versus bone metastasis

Cancers that originate in the bones are called primary bone cancers.

In most cases of adults with any bone cancer types, cancer starts somewhere else and then spreads to the bones: this is called bone metastasis and this can develop from different types of advanced cancers like breast, lung, and prostate cancer. If you observe cancer cells in the bone with a microscope; you’ll find they look like the cancer cells in the organ they came from.

Types of primary bone cancers

Primary bone cancers (cancers that begin in the bone itself) are also called bone sarcomas.

There are many kinds of primary bone cancer and some of them are rare.

Osteosarcoma

Osteosarcoma (or osteogenic sarcoma) is the most commonly found primary bone cancer. It starts in an early form of bone cells and often occurs in young people between the 10 and 30, whereas about 1 in 10 osteosarcomas develop in people above 60: it is very rare in middle-aged people, and is more common in men. These develop mostly in the bones of the arms, legs, or pelvis.

Ewing tumour (Ewing sarcoma)

These are the second most common type of primary bone cancer found in children, teens, and young adults, and the third most common bone cancer. These rarely occur in adults older than 30. Most Ewing tumours develop in the bones, but they can start from other tissues and organs. The most common sites cancer are the hip (pelvic) bones, the bones in the chest wall (the ribs or shoulder blades), the bones of the spine, and the long bones of the legs.

Chondrosarcoma

Chondrosarcoma begins in early forms of cartilage cells and is the second most common primary bone cancer. It’s uncommon in people under 20, and the risk of chondrosarcoma rises as people get older.

Chondrosarcomas can begin in any place where there’s cartilage. Most develop in bones like the pelvic (hip) bones, legs, or arms and some others begin in the trachea, larynx, chest wall, shoulder blades, ribs, or skull.

High-grade undifferentiated pleomorphic sarcoma (UPS) of bone

This was previously known as malignant fibrous histiocytoma (MFH) of bone. Undifferentiated pleomorphic sarcoma (UPS) usually starts in soft tissues (connective tissues like ligaments, tendons, fat, and muscle). It’s rarer in bones, but if it does occur, it usually afflicts the legs (around the knees) or arms. This cancer mostly occurs in elderly and middle-aged adults and is very rare in children. It tends to grow locally, but sometimes it can spread to other parts of the body.

Fibrosarcoma of bone

Another from types of bone cancer that develops more often in soft tissues than in bones usually occurs in middle-aged adults. Bones in the legs, arms, and jaw are mostly affected.

Giant cell tumor of bone

This type of primary bone cancer can be benign (non-cancerous) or malignant and these tumors are most common in people between their 20s and 30s.

Giant cell bone tumours typically hit the legs (usually near the knees) or arms. They don’t usually spread to distant parts of the body, but after surgery they can recur (even more than once) in the place where they began. With every recurrence, the tumour gets more likely to spread to other parts of the body (most often to the lungs). Rarely will a malignant giant cell bone tumour spread to other parts of the body without first recurring locally.

Chordoma

This uncommon type of bone tumour occurs in the bones of the spine, mostly at the bottom of the spine (sacrum) or the base of the skull. It happens most often to adults older than 30 and is twice as common in men as in women and very rarely does it occur in children.

Chordomas usually grow slowly and don’t spread to other parts of the body and often come back in the same area if they are not removed completely.

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The various types and causes of bone cancer explained…

Though rarer than most types of cancer, the risk is highest for those between 10 and 30 years of age, particularly during a teenage growth spurt. This could mean a link between rapid bone growth and the risk of developing tumors. The risk does decrease with middle age but again rises in older adults (usually over the age of 60).

We’ve constantly provided the best treatment for cancer in South Delhi for the best part of two decades, and we also provide treatment for bone cancer in Delhi, with our oncology departments are comprised of the best cancer doctors in Delhi. If you are looking for treatment for bone cancer in Delhi, this article could be of some help.

Bone cancer happens when a tumor forms in a bone. A tumor could be malignant; it’s growing aggressively and spreading.

A malignant tumor is often referred to as cancerous. Cancer that begins in the bones is rare.

Types

Primary bone cancers are the most serious of all bone cancers. They form directly in the bones or surrounding tissue.

Cancer can also spread ( or metastasize), from another part of your body towards your bones. This is secondary bone cancer, and this type is more prevalent than primary.

The Common types of primary of bone cancer are:

Multiple myeloma (MM)

Multiple myeloma is the most prevalent form of bone cancer, this happens when cells grow in the bone marrow and cause tumors in other bones. MM will usually affect older adults.

Among bone cancers, MM has one of the best outlooks, and many people who have it www won’t need treatment.

Osteosarcoma (Osteogenic sarcoma)

Osteosarcoma generally affects children and adolescents, but it can also include adults. It usually originates at the tips of the long bones in the arms and legs.

Osteosarcoma may also start in the hips, shoulders, or other locations. It affects the hard tissue that provides the outer layer of your bones.

Chondrosarcoma

Chondrosarcoma can occur in the pelvis, thigh areas, and shoulders in older adults.

It forms in the tough connective tissue between your bones. This is the second most common primary cancer.

Ewing’s sarcoma

A much rare cancer that either begins in the soft tissues surrounding the bones or directly in the bones of children and young adults.

The long bones of the body — such as the arms and legs — and the pelvis are commonly affected.

What are the symptoms of bone cancer?

The symptoms of bone cancer are:

Less common symptoms include:

What causes?

The exact cause of bone cancer isn’t known to us, but there are some factors that may increase the chances.

These are:

Abnormal cellular growth

Healthy cells continually divide and replace older cells. After completing this process they die. Abnormal cells, however, continue living. They start forming masses of tissue that turn into tumors.

Radiation therapy

Radiation therapy, which kills dangerous cancer cells, can be used to treat bone cancer. However, osteosarcoma may form in some people who receive the treatment. The use of high doses of radiation may be a factor in this development.

Who is at risk ?

The following may be risk factors for bone cancer:

About bone cancer

Bone cancer occurs when cells in the bone begin to divide uncontrollably and abnormally. Bone cancer can affect any bone in the body, but it most commonly affects the pelvis or the long bones in the arms and legs including thigh bone, knee bone. Bone cancer is a rare type of cancer
Bone cancer is rare-less than 1 percent of all cancers, in addition, bone cancer is not a type of cancer that begins elsewhere in the body and spread to the bone.
There are several treatment options available to cure bone cancer at Oncoplus Hospital, Delhi.

Types of bone cancer


Bone cancer is classified into certain types based on the type of cell where the cancer began. The types of bone cancer include:

  1. Osteosarcoma: Osteosarcoma is the most common form of bone cancer. In this type, the tumor or cancerous cells form osteoid or bone.
    • Primary Osteosarcoma: Tumours that occur between the ages of 15-25 years and affect the sites commonly- the lower-end of the femur; the upper end of the tibia; and the upper end of the humerus.
    • Secondary Osteosarcoma: When a premalignant disease affects a bone and develops cancer is termed as secondary osteosarcoma. This type affects people above 45 years.
    • Parosteal Osteosarcoma: This type of cancer begins in the region of periosteum.
  2. Chondrosarcoma: In this type of cancer, the tumor or cancerous cells form cartilage and commonly occurs in the pelvis, legs or arms but is common in flat bones such as ribs, scapula, and ribs.
  3. Ewing sarcoma: Ewing sarcoma tumors occurs in long bones like tibia and femur and less commonly in flat bones like pelvis. It is more common in teenagers and young adults.
  4. Fibrosarcoma: Fibrosarcoma is a rare type of cancer that affects cells known as fibroblasts, which are responsible for creating fibrous tissue throughout the body like in tendons(which connect muscle to bone) and other soft tissue like ligaments or muscle.

Signs and Symptoms of Bone Cancer

  • Pain in the affected bone
  • The affected area may develop swelling and lumps
  • Fractures due to weakened bones
  • Numbness or a tingling sensation in affected area
  • It may cause unintentional weight loss and fatigue
  • Difficulty during movement

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Diagnosis:

Imaging tests can help determine the location and size of bone tumors, and whether the tumors have spread to other parts of the body.

The doctor may advise multiple blood tests to inspect overall general health. Other tissues may include:

  • X-ray
  • Computed tomography scan
  • Magnetic resonance imaging (MRI)
  • Positron emission tomography (PET) scan
  • Biopsy: A procedure in which tissue samples are removed with a needle or during surgery from the body for examination under a microscope.

WHAT ARE THE CAUSES AND RISK FACTORS OF BONE CANCER?

  1. Age: Cancers usually appear with age. But in some types of cancers, younger people have a higher risk of developing them.
    Osteosarcoma is common in teenagers and young adults and is associated with the growth of bones during puberty. It may also appear in older people.
    Spindle cell sarcomas and chondrosarcomas tend to occur in adults between ages 35 and 40 while chondromas occur in adults over 60 years of age.
  2. Radiation therapy or chemotherapy: People who have received radiation or chemotherapy previously run the risk of developing bone cancer, even though it is negligible. If it does occur, it is usually 10-20 years after having radiotherapy. People previously treated with certain chemotherapy drugs might have an increased risk of developing secondary cancer like osteosarcoma.
  3. Individuals with non-cancerous (benign) bone tumors: Paget’s disease of the bone is a benign condition that causes painful and deformed bones. It mostly occurs in people older than 60 years of age, which results in the formation of abnormal bone tissue. The bones affected are usually dense, thick, brittle and weak. They may be susceptible to a fracture.
  4. Genetic disorders: People who have inherited a gene that is maladaptive to the bones may run the risk of developing bone cancers. Hereditary retinoblastoma is a rare eye cancer affecting children. They are more susceptible to develop bone cancer (osteosarcoma), soft tissue sarcomas and other cancers.
  5. Bone Marrow Transplant: Bone marrow transplant is a procedure that replaces bone marrow that is malignant due to infection or chemotherapy. In such cases, there has been an increased risk for developing bone cancers.

WHAT ARE THE STAGES OF BONE CANCER?

Once cancer is diagnosed, tests are recommended to determine the stage of the cancer. Staging is done to find out the severity and extent of cancer spread. Staging helps the specialists to formulate the plan of treatment.

Bone Cancer Treatment Options


The treatment options of bone cancer are based on the type of cancer, the stage of the cancer, patient’s general health. Different bone cancers respond to different treatments, for example, some bone cancers are treated through surgery; some with combination of surgery and chemotherapy; while some with surgery, chemotherapy and radiation therapy.

Chemotherapy in the Treatment of Bone Cancer

Primarily, chemotherapy uses the drugs to destroy the cancerous cells. Chemotherapy drugs are usually delivered through a vein. A few of its primary functions are to starve cancer cells, impede their cell division, and triggering their suicide. While side effects remain, there is an attempt to research drugs that will minimize adverse effects, which are, nausea, weakness, fatigue, bowel-related issues, and blood-related issues, etc.

Radiation Therapy

In Radiation therapy the cancer cells are destroyed using high powered energy radiations. Radiation therapy is often used before an operation because it can shrink the tumour size and make it easier for the surgeon to remove.
Radiation therapy may also be used in patients with bone cancer that cannot be removed through surgery. After surgery, radiation therapy may be used to kill any remaining cancer cells.

Surgery

There are different types of surgery available at Oncoplus Hospital, Delhi for various types and stages of cancer, depending on its size and severity, these are, limb-salvaging surgery, amputation surgery (removal of the limb with affected bone), reconstructive surgery, and surgery for metastasis.
If amputation is needed, you'll likely be fitted with an artificial limb and go through training to learn to do everyday tasks using your new limb.
The goal of surgery is to remove the cancerous tumour completely. In most cases, this involves special techniques to remove the tumor in one single piece, along with a small portion of healthy tissue that surrounds it.

Stem-cell transplants

When Ewing sarcomas are not particularly sensitive to chemotherapy, it may require radiation therapy and perhaps even stem-cell transplants. Stem cell transplants kill bone marrow cells of the affected region, and new cells are induced through the veins to replace destroyed cells through a blood transfusion. Eventually, these new cells adapt to settling down to make healthy bone cells. This process is known as engrafting.

Targeted therapies

Targeted uses drugs to treat cancers but is different from conventional chemotherapy. It works by targeting specific proteins and genes to impede the growth and spread of cancer.
Furthermore, these drugs:

  1. disable the growth and division of cancer cells
  2. prevent cells from living longer than usual
  3. and then, destroy cancer cells

Consult the cancer specialist at Oncoplus Hospital, Delhi.